Dr. Lin is Director and Professor of Biomedical Research Imaging Center, Professor and Vice Chair of Basic Research, Department of Radiology, and Professor of Neurology, and Biomedical Engineering and will serve director with for the Small Animal Imaging core. Dr. Lin has over 20 years of research experience in the area of MRI. He is currently the Director of MR Research, Department of Radiology. His lab consists of two faculty, two post-doctoral fellows, and 5 graduate students. His research area focuses on developing quantitative MR methods for in vivo studies. Specifically, his group has developed imaging methods for obtaining quantitative estimates of blood volume, blood flow, oxygen extraction fraction, cerebral metabolic rate of oxygen utilization, and water content. In addition, the understanding of the underlying biophysical mechanisms of blood oxygen level dependent contrast is also one of the major research areas in Dr. Lin's Lab. Dr. Lin's group has recently further expanded into several different areas including to develop imaging methods for characterizing novel contrast agents, determining bio- distribution of nanoparticles, and the utilization of PET imaging for the study of tissue hypoxia using (64)Cu-ATSM, one of the tracers to be used in the proposed projects. He will work closely with Dr. Hong Yuan, Director of the BRIC Small Animal Imaging Facility to ensure the operation of the Small Animal Imaging core and provide the needed services of the proposed projects.

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